ACTUAL POSITION

07.2020-today:Director of the Intersectional COVID-19 Department, “Sotiria” General
Hospital

05.2014-today: Director of the 3rd Pathology Clinic, School of Medicine of the University of
Athens, “Sotiria” General Hospital.

06.2013-today: Full-time Professor of Pathology and Oncology, School of Medicine of the
University of Athens.

02.2012-today: Adjunct Professor of Medicine, Pittsburgh School of Medicine, with teaching
and research duties.

06.2007-today: Associate Professor of Pathology and Oncology, School of Medicine of the
University of Athens, full-time position.

04.2007-today: Research Associate, Biomedical Research Foundation of the Academy of
Athens (BRFAA)

03.2006-today: Visiting Professor of Thoracic Oncology, Yale Cancer Center, Yale University
School of Medicine, with teaching and research duties.

06.2000-today: Head of the Oncology Unit and the Oncology Laboratory, 3rd Pathology
Clinic of the University of Athens, "Sotiria" General Hospital.
 

PREVIOUS POSTS

09.1997-05.1998: Specialist Registrar, Oncology Clinic, The Royal Hospital NHS Trust, St
Bartholomew's Hospital, Queen Mary and Westfield College, University of London, London,
U.K. (Director: Professor R.T. Oliver, FRCP)

12.1995-08.1997: Registrar, Oncology Clinic, Hammersmith Hospital Campus, Imperial
College of Science, Technology and Medicine, London, U.K. (Director: Professor K. Sikora,
PhD, FRCR, FRCP)

06.1993-11.1995: Senior House Officer (Resident in Oncology) Oncology Clinic,
Hammersmith Hospital Campus. Imperial College of Science, Technology and Medicine,
London, U.K. (Director: Professor K. Sikora, PhD, FRCR, FRCP)

11.1991-05.1993: Resident in Pathology, 1 st Propaedeutic Pathology Clinic of the University
of Athens, Laiko Hospital. (Director: Professor P. Sfikakis, MD).

11.1990-11.1991: Rural Service at the Rural Medical Centre of Agios Myronas, Heraklion,
Crete, Greece.

09.1989-09.1990: Resident in Pathology – Oncology Clinic of the 251 Aviation General
Hospital, Athens (Director: Professor N. Stathakis, MD).

MILITARY SERVICE

Air Force as a Reserve Sub-lieutenant. (26 Sept. 1988- 26 Sept. 1990).

Circular Studies

1970-1976: 1st Primary School of Paleo Faliro, Graduation Diploma: Excellent (10)

1976-1982: Evangelical School of Smyrna, Graduation Diploma: Excellent 19 17/18.

    10.1982: Enrolment at the Athens Medicine School, through National Examinations.
 

Undergraduate Education

10.1982-06.1988: Medicine School of the National and Kapodistrian University of Athens.

30.06.1988: Degree in Medicine, University of Athens, qualification: “Very Good”.
 

Postgraduate Education

30.05.1995: Doctor of the School of Medicine of the University of Athens with the
qualification: “Excellent”.

10.01.1998: Master of Philosophy (M.Phil.), Imperial College of Science, Technology and
Medicine, University of London.

19.05.2000: Doctorate of Philosophy (Ph.D.), Imperial College of Science, Technology and Medicine University of London.

Specialization

 In Pathology, in University Clinics in Greece and abroad:

• 3rd Pathology Clinic of the University of Athens, “Sotiria” Chest Diseases Hospital of
  Athens (November 1991-February 1992; Director: Professor G. Arapakis)..
• 1 st Propaedeutic Pathology Clinic of the University of Athens, Laiko Hospital, Athens
  (February 1992-May 1993; Director: Professor P. Sfikakis)..
• Oncology Clinic, Hammersmith Hospital, Royal Postgraduate Medical School,
  London (June 1993-November 1995; Director: Professor Karol Sikora).
• Diploma of Specialization in Pathology, through examinations before the Athens
  Committee of Pathology, in September 1996 (Chairman of the Committee: Prof. H.M.
  Moutsopoulos).

In Oncology, in University Clinics abroad. Subsequently, he worked as an Oncologist in
recognized university centres abroad.

• Oncology Clinic, Hammersmith Hospital, Royal Postgraduate Medical School,
  London (June 1993-August 1997; Director: Professor Karol Sikora).
• Oncology Clinic, The Royal Hospital NHS Trust, St Bartholomew's Hospital, Queen
  Mary and Westfield College, University of London, London, U.K. (September 1997-
  May 1998; Director: Professor R. T. Oliver).

Diploma of Specialization in Pathology-Oncology, through examinations before the Athens
Committee of Pathological Oncology (September 2003, Chairman of the Committee:
Professor K. Gennatas).
 

Laboratory training

• Participation in the establishment and organization of the Laboratory of Molecular
  Biology of the 1st Propaedeutical Surgical Clinic of “Ippokrateio” Hospital
  (September 1989-February 1992; Director Professor V.H. Golematis).
• Training in immunology methods at the Laboratory of Pathological Physiology, under
  the supervision of Associate Professor Margarita Anapliotou (March 1992-May
  1993; Director Professor A. Fertakis).
• Training in molecular biology, cell culture, radioimmunobiology, radiolabelling and
  laboratory animal handling methods at the Tumour Targeting Laboratory,
  Hammersmith Hospital (June 1993-May 1998; Director Professor AA Epenetos, PhD,
  FRCP) and at the Department of Biochemistry, Imperial College of Science,
  Technology and Medicine (Supervisor: Senior Lecturer M. Deonarain, PhD).

From the above involvement with the laboratory, the following resulted:

1. • His PhD thesis at the University of Athens School of Medicine
   • the Master of Philosophy (MPhil) at the University of London
   • the Philosophy Doctorate (PhD) at the University of London

as well as a sufficient number of international research publications.

FURTHER EDUCATION IN GREECE

Α. Doctoral Thesis

Delivered at the Department of Pathological Physiology of the University of Athens on the
topic: "Study of Adrenal Steroidogenetic Response in Polycystic Ovary Syndrome"
(Supervisor: Professor M. L. Anapliotou). He defended his thesis before a seven-member
examination committee and was awarded the title of Doctor of the School of Medicine of the
University of Athens, with the qualificationExcellent.

Β. Training as an Instructor

1. 1. 1^ο 1. 1 st Training of Trainers Seminar of the Athens School of Medicine, 8 hours,
      Athens 11-12 March 2004.
   2. 2^ο 2 nd Training of Trainers Seminar of the Athens School of Medicine, 4 days,
      Athens 22 & 25-27 June 2004.

FURTHER TRAINING ABROAD

Α. Postdoctoral Dissertation

Delivered at the Imperial College of Science, Technology and Medicine (Departments of
Biochemistry, Clinical Oncology and Histopathology) on the topic: "The Development of a
Prodrug Activation System for the Treatment of Bladder Cancer" (Supervisors: M.
Deonarain, PhD;. AA Epenetos, PhD, FRCP; K Sikora, PhD, FRCP, FRCR). After successful
examinations before a University committee he was awarded the degree of Doctor of Philosophy (Ph.D.).

Total training abroad: 5 years (June 1993-May 1998), of which 19 months after completing
the Pathology specialization.

Β. Post-graduate Seminars

Participation in numerous seminars of the ESO-European School of Oncology, the ESMO-
European Society of Medical Oncology and the ASCO-American Society of Clinical
Oncology. These seminars covered various aspects of Oncology, from basic research to
applied Clinical Oncology.

C. Foreign Languages

English (Excellent)

French(Excellent)

Italian (Proficiency) 

Undergraduate Education:

• Training of students of the School of Medicine of the University of Athens in the
  course of Pathology.
• Head of the elective course “Oncology” at the School of Medicine of the University of
  Athens.
• Training of the 6th and 7th semester students of the School of Medicine of the
  University of Athens in the courses of Clinical Semiology and Nosology.
• Training of the 7th semester students of the School of Medicine of the University of Athens in the courses of Pathology
• Training of the students of the 6th semester of the University of Athens School of
  Dentistry in the course of Semiology.
• Participation in the international educational Exchange Programmes Erasmus and
  DaVinci for students of the University of Athens Schools of Medicine and Nursing,
  respectively.
• Participation in the HELMSIC international Exchange Programme for Medicine
  School students.
• Member of the Studies Committee of the University of Athens School of Medicine

Postgraduate Education:

• & Organizer & Scientific Coordinator of the Postgraduate Studies Programme: “Development of new drugs: research, circulation and access”,, at the School of
  Medicine of the University of Athens.
• Organizer of the Postgraduate Studies Programme:: "Thoracic Oncology: modern
  clinical-laboratory approach & Research", "Thoracic Oncology: modern
  clinical-laboratory approach & Research",
• Coordinator of the course "Oncology: Therapeutic Treatment" in the Master's Degree
  Programme in "Molecular Pathological Anatomy" of the Laboratory of Pathological
  Anatomy of the School of Medicine of the University of Athens (Supervisor:
  Professor E. Patsouris).
• Lecturer in the Postgraduate Programme of Studies on "Stress, Health and Disease" at
  the 1st Pediatric Clinic of the School of Medicine of the University of Athens
  (Supervisor: Professor G. Chroussos).
• Lecturer in the Postgraduate Programme on "Molecular & Applied Physiology" of the
  1st Pediatric Clinic of the School of Medicine of the University of Athens
  (Supervisor: Professor M. Koutsilieris).
• Lecturer in the Postgraduate Programme "Minimally Invasive Surgery" at the School
  of Medicine of the University of Athens (Supervisor: Professor A. Kostakis,
  subsequently Professor Tsigris).
• Lecturer in the Postgraduate Program of Surgery Studies at the Faculty of Medicine of
  the Democritus University of Thrace, during the last 3 years (Supervisor: Professor
  Konstantinos Simopoulos).

Doctoral Dissertations

• Supervising faculty member in twenty-four (24) PhD theses of the School of
  Medicine of the University of Athens.
• Member of the three-member committee in eighteen (18) PhD theses of the School of
  Medicine of the University of Athens.
• Member of the three member committees for PhD theses at the University of Piraeus,
  Panteion University and the Biochemical Department of the University of Athens.

RESEARCH PARTNERSHIPS
• – Biomedical Research Foundation of the Academy of Athens (Scholar Gr. Skalkeas)
• Head and Neck Unit, Royal Marsden Hospital, London, UK (Senior Lecturer Chris Nutting).
• CRC Center for Cell & Molecular Biology, Institute of Cancer Research, London, UK (Senior Lecturer Kevin J. Harrington).

CLINICAL RESEARCH
Professor Konstantinos Syrigos has served as Global and National Principal Investigator in
international multicentre or IIS (Investigator Initiated Studies) Phase I-II clinical trials.
His main research work is the development of new drugs and translational research in
collaboration with international centres in North America and Europe.

In addition, the 3 rd University Pathology-Oncology Unit has a well-organized and ISO
Certified Clinical Studies Office.

He participates in one hundred and fifty-two (152) international multicentre studies
conducted with the approval of the National Organisation for Medicines (EOF) and within
the framework of international Good Clinical Practice (GCP) guidelines.

LABORATORY WORK

• His PhD thesis (M.D.) deals with the study of adrenal steroidogenesis in patients with
  polycystic ovary syndrome and was conducted at the Pathological Physiology Clinic
  and Laboratory (Director Professor H. Moutsopoulos).
• His postdoctoral thesis (Ph.D.) discusses the use of monoclonal antibodies in the
  treatment of tumorous diseases, as carriers of a toxic agent. Specifically, he developed
  a new drug that was a complex of a monoclonal antibody and a toxic agent. The
  efficacy and toxicity of the drug was tested in cell cultures, animal models and led to
  a Phase I Clinical Trial in bladder cancer patients.

Delivered in the Tumour Targeting Laboratory of the Institute of Cancer Research Fund,
Imperial College of Science, Technology and Medicine, University of London (Director
Professor Karol Sicora).

• Associate Researcher of the BRFAA – Biomedical Research Foundation of the
  Academy of Athens, in the field of Clinical Oncology, following the agreement of the
  Athens School of Medicine, the Board of Directors of the BRFAA and the Board of
  Directors of "Sotiria" Hospital
• Visiting Professor of Thoracic Oncology at the Yale Cancer Center, Yale School of
  Medicine, following the agreement of the Athens School of Medicine, the Yale
  School of Medicine and the Oncology Center. As the principal investigator, the main
  focus of his research is:

a) The study of the intracellular EGFR pathway in Lung Cancer and its exploitation for more
effective targeting with newer biologic drugs.

b) Finding reliable molecular markers for the application of immunotherapy in cancer
patients.

• During the years 1989-1993 he participated in the establishment and organization of
  the Laboratory of Immunology and Molecular Biology of the 1st Propaedeutical
  Surgical Clinic of the University of Athens (Director Professor V.H. Golematis).
• Under the guidance of Professor Massimo Pignatelli (Department of Histopathology,
  Hammersmith Hospital) he worked on the tissue expression of adhesion molecules in
  healthy and pathological tissues, with particular interest in investigating the clinical
  relevance of their pathological expression in tumorous diseases.
• Under the guidance of Professor A. A. Epenetos (Department of Clinical Oncology,
  Hammersmith Hospital) he worked on the development of new strategies for cancer
  treatment using Targeted Therapy techniques.
• The Oncology Laboratory was organized and fully equipped within the framework of
  the Oncology Unit of the 3rd University Pathology Clinic, on his own initiative and
  with the contribution of a private person. During the 20 years of its operation,
  methods of molecular biology, immunology and cell culture were developed. A
  method for quantitative measurement of circulating adhesion molecules was
  developed for most of these molecules. Three biologists and one preparator work in
  the Oncology Laboratory under his supervision and postgraduate students and
  physicians are working on their PhD thesis. In recent years, the Oncology Laboratory
  has developed cooperation through research projects with the following renowned
  research centres in Greece and abroad:

• Yale Cancer Center, Yale University School of Medicine (Professor Roy S. Herbst).
• BRFAA – Biomedical Research Foundation of the Academy of Athens (Scholar Gr.
Skalkeas)
• Head and Neck Unit, Royal Marsden Hospital, London, UK (Senior Lecturer Christopher Nutting).
• CRC Center for Cell & Molecular Biology, Institute of Cancer Research, London, UK (Senior Lecturer Kevin J. Harrington).

School of Medicine of the University of Athens

• Director of the Department of Pathology at the School of Medicine of the University
  of Athens from September 2019 until today.
• Director of the 3rd Pathology Clinic of the School of Medicine of the University of
  Athens from 2014 until today.
• Elected member of the General Assembly of the Athens School of Medicine and
  member of the Education Committee during the academic years 2008-2009 & 2010-
  2011 & 2019-present.
• Member of the Education Committee of the General Assembly of the School of
  Medicine during the Academic Years 2010-2011 & 2011-2012 & 2019-present.
• Member of electoral bodies for the election and development of faculty members of
  the School of Medicine of the University of Athens and the other Schools of Medicine
  of Greece.

<strongHellenic Association of Lung Cancer(HeALC)

• Chairman of the Board of Directors

SOS Children’s Villages in Greece

• Chairman of the Board of Directors

Oncology center of Biomedical Research and education (ΟΚΙΒΕΕ)

• Chairman of the Board of Directors

ΙBRFAA – Biomedical Research Foundation of the Academy of Athens

• Member of the Scientific Committee of BRFAA.

“Sotiria” General Hospital

• Director of the 3rd Pathology Clinic of the School of Medicine of the University of
  Athens.
• Director of the COVID-19 Intersectional Unit.
• Chairman of the Oncology Committee of the "Sotiria" Hospital.

National Organization for Medicines (E.O.F.) – National Ethics Committee (NEC)

• Chairman of the Oncology Treatment Protocols Committee of the Hellenic
  Organisation for Medicines.
• Chairman of the Committee for Off-label Medicinal Products of the Hellenic
  Medicines Organisation.
• Rapporteur of the National Ethics Committee for oncology clinical protocols.
• National Representative of the Hellenic Medicines Organisation to the European
  Agency for the Evaluation of Medical Products (EMEA) on ethics committees..

Central Health Council (KESY)

• Member of the Cyberknife & y-Knife Approval Committee of the Central Health Council
  (KESY).
•  Rapporteur of the Central Health Council (KESY) on oncological issues.